Guest:
Dr. Rafi Ahmed is a Professor in the Department of Microbiology and Immunology and the Director of the Emory Vaccine Center at Emory University. He talks about his early work on memory T cells and its applications in autoimmune diseases and cancer.
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The Immunology Round Up
CAR T Therapy for Hemolytic Anemia: CD19 CAR T cells resulted in sustained remission in patients with multirefractory autoimmune hemolytic anemia. (3:05)
How Epstein-Barr Virus and Genetics Drive Multiple Sclerosis: A new study provides a new mechanistic link for how the environmental and genetic risk factors may contribute jointly to multiple sclerosis. (8:30)
Autoantigens in Multiple Sclerosis: EBNA1 CD4+ T cells can target the multiple sclerosis autoantigen anoctamin-2, establishing a link between Epstein-Barr infection and neuroinflammation. (18:45)
Microbiota-Induced T Cell Plasticity: Molecular mimicry between a gut commensal and a tumor antigen can boost the efficacy of immune checkpoint blockade therapy and restrain tumor growth. (26:00)
