Krishna Rao - Anthropic's CFO on Compute, Scaling to $30B ARR, and the Returns to Frontier Intelligence - [Invest Like the Best, EP.471]
Invest Like the Best with Patrick O'Shaughnessy
Mythos Release and Responsible Phased Rollout
Krishna explains Mythos's cyber strength, phased release, and defensive use cases to reduce misuse risks.
My guest today is Krishna Rao, the CFO of Anthropic. The center of our conversation is how he navigates the decision around procuring and allocating compute, which he describes as the canvas on which everything else gets built.
We talk about what he calls the cone of uncertainty, the three chip platforms Anthropic uses fungibly across Trainium, TPUs, and GPUs, and the daily meetings they run to allocate compute between model development, internal use, and serving customer demand.
He explains why the returns to frontier intelligence keep getting higher, especially in enterprise, and how Anthropic thinks about the line between platform and application and why they choose to build their own products like Claude Code.
Krishna has such a unique seat watching one of the fastest growing businesses in history, and he is generous in sharing what he has learned since joining the company two years ago.
For the full show notes, transcript, and links to mentioned content, check out the episode page here.
-----
Become a Colossus member to get our quarterly print magazine and private audio experience, including exclusive profiles and early access to select episodes. Subscribe at colossus.com/subscribe.
-----
Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Go to ramp.com/invest to sign up for free and get a $250 welcome bonus.
-----
Trusted by thousands of businesses, Vanta continuously monitors your security posture and streamlines audits so you can win enterprise deals and build customer trust without the traditional overhead. Invest Like the Best listeners get a special offer of $1,000 off Vanta when you go to vanta.com/invest.
-----
WorkOS is the infrastructure B2B and AI-native companies use to sell to enterprise. It covers everything enterprise security requires: SSO, SCIM, RBAC, Audit Logs, AI governance, and more. Trusted by 2,000+ fast-growing companies, including OpenAI, Anthropic, Cursor, and Vercel.
-----
Rogo is the AI platform for finance. They're building agents for Wall Street that are trained to understand how bankers and investors actually do work: from diligence and modeling, to turning analysis into deliverables. To learn more, visit rogo.ai/invest.
-----
Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. Visit ridgelineapps.com.
-----
Editing and post-production work for this episode was provided by The Podcast Consultant (https://thepodcastconsultant.com).
Timestamps:
(00:00:00) Welcome to Invest Like The Best
(00:02:29) Episode Intro: Krishna Rao
(00:03:14) Compute as Anthropic's Lifeblood
(00:05:17) Three Fungible Chip Platforms
(00:07:31) The Cone of Uncertainty
(00:09:08) Competing Ways to Allocate Compute
(00:10:36) What Drives Compute Efficiency
(00:12:38) Why Frontier Returns Are So High
(00:16:32) How Claude Code Writes Its Own Code
(00:18:46) Will Talent Become Obsolete?
(00:20:07) How Scaling Laws Are Holding
(00:21:54) Exponential Thinking
(00:23:17) The Layer Cake of Compute
(00:26:36) How Anthropic Deploys New Compute
(00:27:53) Platform v. Application Layer
(00:32:42) Why Model Pricing Has Stayed Stable
(00:35:26) Measuring Return on Compute
(00:37:22) Working With Chip Providers
(00:38:32) How Anthropic's Finance Team Uses Claude
(00:41:32) The Jevons Paradox for Labor
(00:43:08) Anthropic's Fundraising & Growth Journey
(00:47:31) The Exponential Revenue Curve
(00:49:02) The Hardest Thing to Explain to Investors
(00:52:15) AI's Public Perception Problem
(00:55:38) Mythos
(00:57:31) Relationship With Government
(00:58:51) Inside Anthropic's Culture
(01:03:48) The Next Frontier: Virtual Collaborators
(01:06:22) How Leaders Scale With a Business
(01:10:55) The Biggest Risks to Continued Progress
(01:12:09) What Krishna is Excited About
(01:13:45) The Kindest Thing
The AI-powered Podcast Player
