Is There a Good Theory?

In electro physiology methods, whether stimulating or recording, you're often looking at a sparse subset of cells. But when it comes to controlling the system, i think it's not obvious that access to only a small number of nodes will allow you to drive the system. How do we know how many neurons we need access to to actually drive the system into the modes that we're looking for? Is a great question. It depends n on where in the pipe line you are, right? So if you're way over on the sensory side, versus way over onthe motor side, versus somewhere in the middle a, you're going to see very different things.

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Episode notes

Welcome back to Neurotech Pub!

This episode is part two of a two part series on optical methods for recording and stimulating neural activity. Our guests on this episode are Elizabeth Hillman, PhD, Mark Schnitzer, PhD, and Jacob Robinson, PhD. Last time we talked about optical recording methods, but in this episode we focus on optical stimulation methods.

Cheers!

Check out video and full transcript here: https://www.paradromics.com/podcast/episode-12-mind-control-with-lasers

00:00 | Intro

1:37 | Aspirational Papers

1:56 | Packer Lab

2:10 | What is the claustrum?

2:30 | Ian's paper (but only part of it!)

3:02 | Two-Photon Bidirectional Control and Imaging In Vivo

3:29 | Inferring Spikes from Calcium Imaging

5:45 | Neuropixels are now in humans

7:12 | Paper by Pachitariu et al

7:55 | Ian Oldenburg