How Women Can Improve Their Fertility & Hormone Health | Dr. Natalie Crawford
Huberman Lab
PRP and Paternal Age Raise Nuanced Tradeoffs
Natalie Crawford reviews uterine versus ovarian PRP, advanced paternal age, and why optimizing sperm health still matters even when risks remain relatively low.
Dr. Natalie Crawford, MD, is a double board-certified OB-GYN and reproductive endocrinologist. We discuss how to improve hormone health at any age and the importance of fertility markers not just for pregnancy, but as a powerful window into overall health, vitality and longevity. We discuss hormone replacement therapy, egg freezing, IVF, and what biomarkers like AMH really indicate. Plus, how anti-inflammatory diets and specific supplements can be beneficial and the impact of microplastics and certain fragrances on hormones. We also discuss lesser-known factors that deplete male and female fertility, vitality and health. This conversation highlights how better understanding of hormones and your reproductive markers can empower better informed choices at every stage of life.
Read the show notes at hubermanlab.com.
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Timestamps
(00:00:00) Natalie Crawford
(00:02:26) Fertility as a Health Marker, Infertility
(00:05:34) Perimenopause, Menopause, Hormone Replacement Theory
(00:11:01) Sponsors: David & BetterHelp
(00:13:35) Hormone Therapy, Extending Ovarian Lifespan
(00:19:11) Plastics, Toxins & Fertility
(00:22:02) Does Prior Pregnancy Make Conception Easier?, Secondary Infertility
(00:29:02) Testing Sperm; Pregnancy Loss & Conceiving Again, Fertility Testing
(00:38:17) Sponsor: AG1
(00:39:40) Menstrual Cycle, Egg Number & Quality, AMH Test
(00:48:17) Tool: AMH Test; Fertility Education & Patient Choices
(00:53:13) Tool: Tracking Ovulation; Ovulation Disorders
(00:55:11) AMH Test Cost; Genetic Testing & Patient Choice
(01:01:13) Does Egg Freezing Cause Early Menopause?, In Vitro Fertilization (IVF)
(01:05:29) Egg Freezing, IVF, Ethical Concerns; Embryo Banking
(01:15:21) Sponsor: Eight Sleep
(01:16:39) Egg Freezing, Cost & Patient Choices
(01:21:22) Concieving After Hormonal Birth Control, IUD or Depo-Provera
(01:27:17) Pregnancy Termination & Concieving Again
(01:29:28) Support Egg Quality, Tools: Ovulation & Avoiding NSAIDs; 5 Lifestyle Non-Negotiables
(01:34:03) Sleep, Melatonin; Cold Plunge
(01:38:41) Curcumin, NAD/NR, CoQ10, Supplements for Prenatal Care & Sperm Health
(01:42:05) Sponsor: Function
(01:43:16) Fertility Research into Supplements & Lifestyle Factors
(01:48:21) Inflammation, Red Light
(01:53:12) Cannabis & Detriments to Egg & Sperm Health
(01:58:57) Nicotine, Smoking, Egg Health & Sperm Count; Healthy Lifestyle Practices
(02:02:21) GLP-1s, PCOS, Endometriosis; Human Growth Hormone
(02:10:58) Platelet-Rich Plasma; Paternal Age & Sperm Quality; Biotin
(02:17:27) Endocrine Disruptors, Fragrances, Receipts, Tool: Fragrance-Free
(02:22:48) Patient Education & Empowerment; Inflammation, Celiac Disease
(02:25:40) Anti-Inflammatory Diet, Protein, Fiber, Red Meat
(02:33:25) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter
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