Somatic hypermutation selects pathogenic specificity

TWiV explains how vaccine-induced thrombotic thrombocytopenia develops from antibodies to adenovirus and somatic hypermutation, and castration by a viral protein tyrosine phosphatase that targets a host cell cycle checkpoint protein.

Subscribe (free): Apple Podcasts, RSS, email

Become a patron of TWiV!

• Support science education at MicrobeTV
• Positions in Rosenfeld Lab (email)
• US repeals environmental endangerment finding (Nature)
• Environmental groups sue EPA (Guardian)
• NIAID to drop pandemic preparedness and biodefense (Nature)
• FDA backpedals on Moderna mRNA rejection (npr)
• Mechanism of VITT (NEJM)
• Parasitc castration by a wasp virus protein (PNAS)
• Polydnaviruses (PloS Path)
• Timestamps by Jolene Ramsey. Thanks!

Brianne – The effect of seeing scientists as intellectually humble on trust in scientists and their research Rich – The Great Bridge: The Epic Story of the Building of the Brooklyn Bridge by David McCullough Alan – Recipes from the American South, by Michael Twitty Vincent – Why Returning From Mars ls Impossible – Richard Feynman’s Warning Intro music is by Ronald Jenkees

Send your virology questions and comments to twiv@microbe.tv

Content in this podcast should not be construed as medical advice.