Microplastics as hormone disruptors and fat storage

Microplastics are invading your brain, blood, hormones, and fat tissue, and most people have no idea how deep the damage goes. In this episode, Host Dave Asprey and microplastics expert Josephine Musco break down exactly what these particles are doing inside your body and give you a practical, science-backed action plan to detox, protect yourself, and take back control of your biology. 

-Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR 

-Get a discount on Olyxir Tea by going to https://www.olyxir.com/ and using code ‘Dave10’ at checkout 

Josephine Musco is a multidisciplinary entrepreneur, Demeter-certified biodynamic farmer, and winemaker at Chateau Bellevue 1881 in Livermore, California. She is the founder of Olyxir Tea Strips and holds two scientific patents rooted in her deep expertise in botanical medicine and regenerative health. She is best known for translating complex research on aging, nutrition, environmental toxins, and functional medicine into practical daily habits, and for her work exposing microplastics and PFAs as one of the most underestimated drivers of accelerated biological aging. 

Dave Asprey and Josephine cover the full picture: how nanoplastics cross the blood-brain barrier and accumulate in postmortem brain tissue, how endocrine disruption from plastics tanks testosterone and drives fat storage, and why your teabag, canned soup, and yoga pants may be among your biggest sources of daily exposure. They also go deep on real solutions, from lymphatic drainage protocols and infrared sauna to supplements like chlorella, lactobacillus, and olive leaf polyphenols that actively help the body clear microplastics and support longevity and brain optimization. 

This is essential listening for anyone serious about biohacking, anti-aging, metabolism, brain optimization, supplements, human performance, and smarter not harder approaches to living clean in a toxic world. If you drink tea, cook with plastic utensils, or wear synthetic workout clothes, this episode will change how you make decisions every single day.  

You'll Learn: 

• Why 0.5 percent of postmortem brain tissue is now made of microplastics and what that means for neuroplasticity and cognitive decline 
• How microplastics mimic estrogen, disrupt metabolism, and make it nearly impossible to lose fat 
• The link between microplastic plaque in carotid arteries and a 4.5x increased risk of cardiac events 
• Which everyday sources, including teabags, canned soup, cookware, and plastic cutting boards, are silently loading your body with nanoplastics 
• How lactobacillus reduced microplastics in the blood by 82 percent in studies, and which other supplements support detox 
• Why Dave Asprey drinks Danger Coffee from a metal container and what his full microplastic reduction protocol looks like 
• How olive leaf polyphenols, with 26,215 micrograms per gram, act as powerful free radical scavengers to support brain optimization and anti-aging 
• The morning lymphatic activation routine that combines rebounding, herbal strips, and whole body vibration for deep cellular detox 
• Why AI and citizen science are accelerating our understanding of microplastic damage faster than traditional medicine 

Thank you to our sponsors!   

• The One Device | Use code DAVE for $10 off at http://theonedevice.com/dave
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Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living. 

New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient. 

Keywords: microplastics, nanoplastics, teabags, detoxification, BPA, endocrine disruptors, brain health, fertility, reproductive health, Josephine Musco, Elixir Tea Strips, sauna detox, infrared sauna, lymphatic system, probiotics, polyphenols, olive leaf, toxins, heavy metals, pesticides, plastic contamination, water bottles, non-stick cookware, synthetic fabrics, inflammation, Alzheimer's, dementia, cognitive decline, testosterone, preconception health, pregnancy, longevity, anti-aging, biohacking, functional medicine, Dave Asprey, environmental toxins, detox protocols, gut health, acacia gum, chlorella, spirulina, whole-body vibration, rebounding 

Resources:   

• Get a discount on Olyxir Tea by going to https://www.olyxir.com/ and using code ‘Dave10’ at checkout 

• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-clean-nicotine-roadmap/ 

• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.  

• Danger Coffee: https://dangercoffee.com/discount/dave15   

• My Daily Supplements: SuppGrade Labs (15% Off)   

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)   

• Dave Asprey’s BEYOND Conference: https://beyondconference.com   

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated  

• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/ 

• Upgrade Labs: https://upgradelabs.com   

Timestamps: 

00:00 – Introduction 

03:00 – Microplastics in the Brain 

08:40 – Olyxir Tea Strip Solution 

10:10 – Health Impacts & Weight Gain 

11:05 – Environmental Solutions 

14:29 – The Teabag Problem 

18:57 – How to Remove Microplastics 

22:04 – Olive Leaf Benefits 

28:26 – Josephine's Scientific Background 

33:00 – Guarana & Lymphatic Support 

34:22 – Skincare & Microplastics 

36:38 – Sauna Protocol 

44:19 – Household Exposure Sources 

47:18 – Workout Clothing Risk 

48:59 – Leather vs Synthetic Fashion 

50:54 – Pregnancy & Fertility 

54:20 – Closing & Discount Code 

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