Diabetes has been recognised as a fatal condition for thousands of years: its symptoms are described in ancient Chinese, Sanskrit and Greek texts. But it wasn’t until the late 19th century that its cause began to be understood, as scientists conducted experiments on dogs. It was a pair of researchers at the University of Toronto in the early 1920s who – through a gruelling series of experiments that would not pass an ethics review today – eventually isolated the hormone that patients with diabetes are lacking.
On this episode, Liam Shaw, who reviewed the latest edition of Michael Bliss’s classic book The Discovery of Insulin in a recent issue of the LRB, joins Thomas Jones to discuss the history of diabetes treatments from insulin to Ozempic, the all-too-human scientists who discovered them and the companies that profit from them.
Read Liam’s piece: https://www.lrb.co.uk/the-paper/v48/n06/liam-shaw/bring-me-bimagrumab
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