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Muscle Relaxants and their speed of onset

Anaesthesia Coffee Break

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What Do You Think About Volume Distribution in Pharmacokinetics?

Instead of saying time for transport from site of injection to muscle, what I think you should write is kinetics, dose to plasma concentration. Then he's got a very similar idea to what you have written last. He's included some of the factors that you put in pharmacodynamics in pharmacokinetics. So if you know every time you say kinetics, you're going to do absorption distribution and you invoke things like protein binding and volume, it's like it's no extra memory. Plus blood volume comes into volume of the stream, but so does protein binding. So does fat.

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