Intro

Special Guests: Matthew Semler, MD &

Nicole Acquisto, PharmD, FASHP, FCCM, FCCP

Join us as we do a deep dive into the RSI trial, published in NEJM in Dec 2025.

Previous RCTs, study development timeline, guideline recommendations, study methodology and findings, answering listener questions, clearing up internet rumors, how to apply these findings, significant secondary outcome?, next steps, fun facts, and so much more.

RSI Trial: https://pubmed.ncbi.nlm.nih.gov/41369227/

Episode Reference List: https://pharmacytodose.wordpress.com/wp-content/uploads/2026/01/rsi-trial-deep-dive-references.pdf

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