Trial design and population

Happy New Year! This month for the January 2026 episode of the RCEM Learning Podcast Andy and Dave discuss two papers with Dave - looking at the role of CT scanning in undifferentiated sepsis and the use of bicarbonate in acidaemia. Rob talks to Ben Clarke and Ryan McHenry about the latest TERN Study, the UnCORKED Study, and we then end with New Online! If you'd like to email us, please feel free to do so here. After listening, complete a short quiz to have your time accredited for CPD at the RCEMLearning website!

(01:59) New in EM - CT in sepsis

• Suspected infection of unclear origin at the emergency department: diagnostic yield of thoraco-abdominal-pelvic CT in non-severe patients (Dumon et al., 2025)

(16:16) Ben Clarke and Ryan McHenry - The UnCORKED Study

• Understanding corridor and escalation area care in 165 UK emergency departments: a multicentre cross-sectional snapshot study (TERN, 2025)
• TERN Research

(38:59) New in EM - Bicarbonate in acidemia

• Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury: The BICARICU-2 Randomized Clinical Trial (Jung et al., 2025)

(50:00) New Online – new articles on RCEMLearning for your CPD

• Frances Copp - The Droopy Dribbler
• Frances Balmer - Methaemoglobinaemia
• Sarah Edwards - Genitourinary Foreign Bodies