Virtual immune system and cellular engineering

They highlight modeling the immune system, CAR-T approaches, engineered cells, and clinical opportunities from immune understanding.

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Episode notes

This crossover episode from the Latent Space podcast features Mark Zuckerberg and Priscilla Chan on the 10-year anniversary of the Chan Zuckerberg Initiative and their expanded Biohub vision. They discuss how a “Frontier Biology Lab” working in sync with a “Frontier AI Lab” could enable breakthroughs like a Virtual Cell and true N-of-1 precision medicine. The conversation covers the acquisition of Evolutionary Scale and ESM3, new biological data collection at scale, and how AI-powered biology might transform drug discovery and disease prevention.

Sponsors:

Blitzy:

Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com

Framer:

Framer is an enterprise-grade website builder that lets business teams design, launch, and optimize their.com with AI-powered wireframing, real-time collaboration, and built-in analytics. Start building for free and get 30% off a Framer Pro annual plan at https://framer.com/cognitive

Serval:

Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive

Tasklet:

Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai

Claude

Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at ⁠⁠https://claude.ai/tcr⁠

CHAPTERS:

(00:00) About the Episode

(04:27) CZI origins and focus

(08:29) Why tools over cures

(14:43) Virtual cells and imaging (Part 1)

(20:19) Sponsors: Blitzy | Framer

(23:24) Virtual cells and imaging (Part 2)

(25:22) Data diversity and grounding

(32:30) Evaluating models and Biohub (Part 1)

(37:53) Sponsors: Serval | Tasklet

(40:42) Evaluating models and Biohub (Part 2)

(41:06) Future healthcare and aging