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Diffusion and perfusion limited gases and diffusing capacity

Anaesthesia Coffee Break

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Is Perfusion or Diffusion Limited?

Oxygen is normally fully equilabrated when that red blood cell has travelled a third of the way along the capillary, it's not usually perfuse. It doesn't usually become diffusion limited, just with exercise. But imagine there's something else going on. And then if you combine any of these other factors together, suddenly, a profusion limited gas like oxygen can become diffusion limited. At altitude naa oxygen partial pressure loolls as much as 50 milliometers and down. Therefore, now diffusion occurs far slower, and oxygen may become diffusionlimited. The final thing to mention then is the transit time to blood s. That is obviously not in fixed law of diffusion,

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