Alzheimer’s Through a Mitochondrial Lens

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!

This episode is brought to you by:

• Eight Sleep Pod Cover 5 sleeping solution for dynamic cooling and heating: EightSleep.com/Tim
• AG1 all-in-one nutritional supplement: DrinkAG1.com/Tim
• Cresset family office services for CEOs, founders, and entrepreneurs: CressetCapital.com/Tim

Timestamps:

• [00:00:00] A meditative start.
• [00:02:19] Reflecting on our second Zen retreat in Santa Fe with Henry Shukman.
• [00:04:08] Ketone liver warnings and eggplant allergies: The perils of raiding Kevin’s fridge.
• [00:08:06] “Just be still” — three simple words that miraculously shut down my OCD.
• [00:13:54] Is meditation secretly vagus nerve stimulation?
• [00:20:17] DIY vagus nerve stim for $25 vs. Kevin’s $900 ear clip.
• [00:24:57] HeartMath and watching your HRV move in real time.
• [00:27:57] Marching toward 50: balance boards and the end of jiu-jitsu.
• [00:31:26] Tony Hawk snowboarding Hokkaido with screws in his hip.
• [00:33:01] Slacklining and why your nervous system needs sleep cycles.
• [00:35:19] Bertolotti’s Syndrome: My six-year back pain gets a name.
• [00:37:09] The nerve block test: everything wrong, zero pain.
• [00:44:10] Abrahangs tendon protocol: 10 seconds on, 50 off.
• [00:46:24] The NUG: a pocket hangboard for travelers.
• [00:48:31] Craig Mod’s Japanese toothbrush and Toaster’s cameo.
• [00:50:45] Kevin’s $92 vintage fire jacket: Blue Heritage Japan.
• [00:54:26] Podcast picks: The Power Broker and STEM Talk.
• [00:56:20] Alzheimer’s: A plaque or mitochondrial problem?
• [00:57:30] 10 grams of ketones turns one-word answers into sentences.
• [00:58:40] Methylene blue on Amazon: 120 years of research, zero guardrails.
• [01:02:36] Bredesen Protocol, APOE genotyping, and a cognitive comeback.
• [01:05:32] Photobiomodulation: $30k laser to the forehead.
• [01:07:55] Urolithin A and the high price of mitochondrial upkeep.
• [01:14:56] Recipe for disaster pants: espresso + creatine + MCT oil.
• [01:17:39] Norwegian 4×4 training and lactate as a brain lever.
• [01:23:15] Blood flow restriction bands and schwantz ring koans.
• [01:29:08] Hummingbirds named Sunset and squirrel obstacle courses.
• [01:32:06] Parting thoughts.

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