Why Measuring 1,25 Is Crucial

Today's episode is a rerun of one of the most important conversations I've ever shared on the podcast, all about vitamin D. As the podcast library grows, some truly foundational episodes can get buried, and this is information that's simply too important to lose. This is part one of a two-part series, and if you've never listened (or even if you have), it's well worth revisiting. Is your vitamin D "deficiency" actually a misdiagnosis? In this eye-opening episode, Tara dives into one of the most misunderstood nutrients in functional medicine: vitamin D.

While most practitioners rush to prescribe high doses of vitamin D based on a single lab marker (25(OH)D), Tara challenges the status quo and breaks down why this approach can be both misleading and harmful, especially for women in perimenopause.

She explains the critical difference between 25(OH)D and 1,25(OH)₂D, why elevated active vitamin D (1,25) often goes unnoticed, and how it can actually suppress your vitamin D storage while driving up inflammation, calcium loss, and even contributing to autoimmune conditions and bone loss.

This episode is a must-listen if you've ever felt confused about whether to supplement or if you've been taking vitamin D long-term without fully understanding how it works in your body.

• The difference between storage vs. active vitamin D (and why you must always test both but your practitioner likely hasn't)
• The issues with vitamin D testing that scientists are hotly debating (can you even trust your lab result?)
• What is the optimal reference range for vitamin D? And why ranges are terribly inflated and many are not to be trusted.
• What really drives down vitamin D in the body and how to come at this from a root-cause perspective instead of drowning yourself in vitamin D supplements

If you're thinking about taking D, already taking D, or have been told your vitamin D is "low" (it likely isn't) then this one is for you.

🔍 Formula to convert your 25,OH,D leve from ng/dL to nmol/L: 25(OH)D in nmol/L = 25(OH)D in ng/dL X 25

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