Hermetic vs non-hermetic encapsulation explained

Welcome back to Neurotech Pub!

In this episode, host and Paradromics CEO, Matt Angle, speaks with Stuart Cogan, Vanessa Tolosa, Thomas Stieglitz, and Loren Rieth about how to protect neural implants from the harsh environment of the body. This discussion is all about longevity and endurance, and, fittingly, it’s almost 2 hours long. Loren leaves early for a faculty meeting--wonder if his colleagues know that he came straight from the pub?

Check out full video with transcript here: https://www.paradromics.com/podcast/neurotech-pub-episode-3-connectors-cans-and-coatings

03:27 | UTD Neural Interfaces Lab

03:39 | EIC Labs

03:59 | Cogan’s highly-cited review paper

04:16 | Lawrence Livermore National Lab

04:56 | Rieth Lab at the Feinstein Institute

05:18 | Loren’s work with the Utah Array

05:39 | Human peripheral nerve stimulation

05:58 | Preclinical Vegus Nerve stimulation

06:11 | Stieglitz Lab

06:22 | Flexible Electrodes

06:41 | Long Lasting Electrodes

07:41 | Jerry Loeb: Materials Legend

08:29 | Phil Troyk

09:24 | North American Neuromodulation Society

10:44 | Melosh Lab at Stanford

12:53 | Packaging Development

17:02 | Helium Leak Test

19:01  | Work by Pancrazio

21:34 | Finetech-Brindley Stimulator

29:05 | Emerging technology @ University of Sydney

33:10 | Calvin and Hobbes

34:12 | Revolutionizing Prosthetics

35:00 | Canned Utah Array

35:35 | Flip-chip connecting

36:04 | Nick Donaldson: Mr. Clean

36:47 | Failure mode analysis

36:55 | Scaling up the Utah Array

37:54 | DARPA’s NESD Program

38:28 | High density Utah Array

39:52 | The Michigan Probe

40:00 | Vanessa’s work with Loren Frank

42:05 | Parylene C encapsulation

42:56 | Thin film

44:15 | Clean rooms

46:50 | NeuroRoots

47:28| Test structures

49:17 | Implant size

50:35 | Testing strategies

52:40 | NeuroNexus

53:59 | Tissue response studies

54:27 | Cogan Lab’s work on Silicon Carbide

56:10 | DARPA’s HAPTIX Program

56:30 | Reactive Accelerated Aging (RAA)

58:15 | RAA with hydrogen peroxide

58:55 | Deep Brain Stimulation

01:02:55 | Hydrolysis

01:09:00 | Silicon Carbide device

01:10:26 | Neuropixels collaboration

01:19:05 | Atomic Layer Deposition

01:26:55 | Focused research orgs

01:36:14 | Second Sight

01:43:48 | Search for Paradise by Jens Naumaunn

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