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Recon | Wear & Osteolysis Basic Science

The Orthobullets Podcast

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The Properties of Ultra-High Molecular Weight Polyethylene

BMP7 is incorrect, as BMP2, 4, 6, and 7 all exhibit osteoinductive activity. IL10 inhibits osteoclast formation along with calcitonin. Sox9 is a key transcription factor involved in the differentiation of cells towards the cartilage lineage. Osteoportegrin binds to rank L on the osteoclast, preventing rank activation and inhibiting osteoclast activity. Smaller implant diameter associated with elevated serum metal ion levels after hip surgery.

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