Anaphylaxis mediators and acute treatment

By popular demand, here is the actual physiology and pharmacology viva that Stan was examined on for the part 1 ANZCA exam!

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Any questions please email Lahiruandstan@gmail.com

Some links and formulas!

How does it measure cardiac output?

Using thermodilution and utilisation of Stewart Hamilton’s equation of:

(Tb-Ti)*Volume*k/intergration of change in T

What is venous admixture?

Venous admixture is the amount of mixed venous blood that needs to be added to end-capillary blood to account for the difference seen in pO2 between arterial blood and end-capillary blood.

It is calculated using the equation:

Qs/Qt = Cc’O2 – CaO2 / Cc’O2 – CvO2

Alveolar gas equation.

PAO2 = FiO2 (Patm – PH2O) – pCO2/R

 Is there anything else at the end?

Yes there is a correction factor (+F) which is FiO2 * pCO2 * (1-R)/R and this is normally less than 2mmHg.

O2 content = SaO2 * Hb * 1.34 (Huffner’s constant which ideally is 1.39) + pO2 * 0.003

the isoshunt diagram is figure 8 here:
https://erj.ersjournals.com/content/44/4/1023.figures-only

Please rate, post a review and subscribe!

Check out https://anaesthesiacollective.com/education/first-part-exam/ for general information and a collection of model answers

and 
sign up to the ABCs of Anaesthesia facebook group https://www.facebook.com/groups/2082807131964430

and check out the ABCs of Anaesthesia YouTube channel for more content
https://www.youtube.com/c/ABCsofAnaesthesia

If you have any questions, please email Lahiruandstan@gmail.com 

Disclaimer:

 The information contained in this podcast is for medical practitioner education only. It is not and will not be relevant for the general public.

This contains general information about medical conditions and treatments. The information is not advice and should not be treated as such. 

The medical information is provided “as is” without any representations or warranties, express or implied. 

The presenter makes no representations or warranties in relation to the medical information on this video. 

You must not rely on the information as an alternative to assessing and managing your patient with your treating team and consultant.

You should seek your own advice from your medical practitioner in relation to any of the topics discussed in this episode’

 Medical information can change rapidly, and the author/s make all reasonable attempts to provide accurate information at the time of filming. There is no guarantee that the information will be accurate at the time of viewing

 The information provided is within the scope of a specialist anaesthetist (FANZCA) working in Australia.

 The information presented here does not represent the views of any hospital or ANZCA.

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