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Recon | Wear & Osteolysis Basic Science

The Orthobullets Podcast

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Metal on Metal Total Habartherplasty: A Type IV Hypersensitivity Reaction?

T cells dominate the reaction produced by metal on metal articulations, confirming it to be a type IV hypersensitivity reaction. Haskawa conclude that metal sensitivity is not involved in the failure of metal on metal total habartherplasty. The correct answer to this question is five IL10 and Anakinra. All of the following promote osteolysis around orthopedic implants and are paired with the correct inhibitor except Rank-Lagand and Denosumab.

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