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Basic Science | Rheumatoid Arthritis

The Orthobullets Podcast

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Symptoms and Comorbidities of Rheumatoid Arthritis

Rheumatoid arthritis has an insidious onset of morning stiffness and polyarthropathy. The disease is associated with specific HLA loci, that is HLA-DR4 and HLA-DW4. There's an approximately 15% rate of concordance amongst monocygotic twins. On physical exam, you may find subcutaneous nodules in 20% of patients.

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