Defining treatment-resistant bipolar depression

In this episode, we explore pramipexole—a Parkinson's medication—as a promising add-on treatment for treatment-resistant bipolar depression. Could a dopamine agonist be the unexpected solution when standard mood stabilizers and antipsychotics fail? We examine the PAX-BD trial's findings, safety concerns, and practical clinical applications.

Faculty: Kristin Raj, M.D. Host: Richard Seeber, M.D.

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• Treatment-Resistant Bipolar Depression: Is Adjunctive Pramipexole An Option?