Defining the paradox of the organism

In this episode, Xavier Bonilla has a dialogue with Arvid Ågren and Manus Patten about internal conflicts within organisms. They provide an overview of the paradox of the organism, clinical examples of cancer and pregnancy, direct, indirect, and inclusive fitness. They talk about cooperation within an organism, conflict, transmission and trait distorters, price equation, conflict awareness, neo-Darwinian embryology, biology of selfhood, and many more topics.

J. Arvid Ågren is Assistant Professor at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Affiliated Researcher at the Evolutionary Biology Centre at Uppsala University. He is the author of The Gene’s-Eye View of Evolution.

Manus M. Patten is an evolutionary biologist whose research explores the consequences of conflict, both for organisms and for evolutionary theory. He is Teaching Professor in Biology at Georgetown University. They are co-editors of the book, The Paradox of the Organism: Adaptation and Internal Conflict.