#49268
Mentioned in 1 episodes
The Engine That Built Life
— implied subtitle not explicitly given in transcript
Book •
Nick Lane's book examines how energy flow and metabolic chemistry, centered on the Krebs cycle and mitochondria, shape life from its origin to aging and disease.
He argues metabolism and proton/ion gradients are primary drivers, predating genetic systems, and explores hydrothermal vents as plausible origin environments.
Lane connects these biochemical principles to mitochondria's role in eukaryotes, aging, fertility, and cancer metabolism.
The book synthesizes lab findings, evolutionary history, and thermodynamics to propose a transformer-like metabolic core that persists across life.
It aims to reframe life as energy in motion rather than information acting on chemistry.
He argues metabolism and proton/ion gradients are primary drivers, predating genetic systems, and explores hydrothermal vents as plausible origin environments.
Lane connects these biochemical principles to mitochondria's role in eukaryotes, aging, fertility, and cancer metabolism.
The book synthesizes lab findings, evolutionary history, and thermodynamics to propose a transformer-like metabolic core that persists across life.
It aims to reframe life as energy in motion rather than information acting on chemistry.
Mentioned by
Mentioned in 1 episodes
Mentioned by 
Brian Keating
19 snips
Nick Lane: The Engine That Built Life
